Accession Number:

ADA232046

Title:

Modeling of the Laser-Induced Thermal Response, Ablation, and Fragmentation of Biological Tissue

Descriptive Note:

Annual rept. Mar 1987-Apr 1988

Corporate Author:

PHYSICAL SCIENCES INC ANDOVER MA

Report Date:

1988-04-27

Pagination or Media Count:

75.0

Abstract:

This report describes the modeling activities carried out by Physical Sciences Inc. PSI during the first year of our ONR Contract N0014-87-C-0161. The objective of this contract is to develop models which can ultimately be used to predict the thermal response, ablation, and fragmentation of hard and soft biological tissue exposed to free electron laser FEL radiation. Most of our efforts thus far have been focused on the hard tissue problem, i.e., kidney stones, gallstones, calcified plaque. During this first year of the program modeling efforts have been initiated in four principal areas 1 further development and application of 1-D and 2-D numerical heat conduction codes to model the thermal damage and ablation of soft tissue exposed to infrared laser energy, 2 modeling of plasma initiation mechanisms in, and resulting plasma spectral emissions from, pulsed laser-irradiated kidney stones and gallstones, 3 modeling of laser-driven shock-induced fragmentation of kidney stones and gallstones, and 4 modeling of the above surface hydrodynamics, i.e., bubble growth and acoustic wave propagation, resulting from plasma-mediated laser energy deposition above a hard tissue surface in a fluid medium.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE