Human Immune Responses to HTLV-III Virus Infections in the Acquired Immunodeficiency Syndrome
Annual rept. Oct 1987-Oct 1988
MASSACHUSETTS UNIV MEDICAL SCHOOL WORCESTER
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The purpose of the research program is to define immune responses of humans to Human Immunodeficiency Virus HIV infection and the cause of the Acquired Immune Deficiency Syndrome AIDS. Immunodeficiency caused by HIV infections may be due to immune mediated lysis by antibody andor HIV specific cytotoxic T lymphocytes CTL of infected macrophages and T4 lymphocytes. The definitions of these immune responses to HIV virus are needed for rational approaches for therapy and prevention. Since the project began in October, 1986, we have developed an integrated program of research projects to develop experimental systems required for defining the immune responses of humans to HIV.
- Medicine and Medical Research