Accession Number:

ADA230423

Title:

An Analysis of the Effects of Phenytoin in Treating Motion Sickness and the Effects of Motion Sickness on the Human Electroencephalogram

Descriptive Note:

Master's thesis

Corporate Author:

AIR FORCE INST OF TECH WRIGHT-PATTERSON AFB OH SCHOOL OF ENGINEERING

Personal Author(s):

• Banducci, Todd M.

Report Date:

1990-12-01

Pagination or Media Count:

258.0

Abstract:

This research had two goals to continue the ongoing research at AFIT to determine the efficacy of the anticonvulsant drug phenytoin in combating the onset and progression of motion sickness and to note whether or not there is a discernable similarity in the brains of the test subjects to indicate a common point of origin epicenter and propagation pattern of the effects of motion sickness in the brain. Eight male DOD personnel were used as subjects to complete twelve trials. Four subjects completed the phenytoin verses placebo double-blind crossover experiment. These four subjects experienced a 99 mean increase in their free-time-to-emesis and a 613 mean increase in their symptom-free-times, with one subject remaining asymptomatic throughout his phenytoin trial. js

Descriptors:

• *TEST AND EVALUATION
• BRAIN
• ELECTROENCEPHALOGRAPHY
• PATTERNS
• EPICENTERS
• MOTION SICKNESS
• PROPAGATION
• HUMANS

Subject Categories:

• Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE