Accession Number:

ADA229426

Title:

Sleep Disturbances at High Altitude. Role of a PCO2 Apneic Threshold

Descriptive Note:

Final rept. 14 Jun 1985-15 Jun 1987,

Corporate Author:

COLORADO UNIV HEALTH SCIENCES CENTER DENVER

Personal Author(s):

Report Date:

1990-06-09

Pagination or Media Count:

13.0

Abstract:

This study addressed the issue as to how exposure and subsequent acclimatization to high altitude influences ventilatory control during wakefulness and sleep and considers the potential implications of such changes for adjustment to high altitude. Specifically, it has been known for some time that during several days exposure to high altitude there occurs a steady, progressive rise in ventilation, the origins of which have been the subject of extensive controversy. Under these same conditions, it is also known that sleep disturbance associated with periodic breathing is common. To further investigate these issues, we studied six healthy males at sea level an on nights 1, 4, and 7, after arrival at high altitude 14,110 feet. During wakefulness, ventilation and the ventilatory responses to hypoxia and hypercapnia were measured, and during both non-rapid-eye-movement and rapid-eye-movement sleep, ventilation, ventilatory pattern and hypercapnic ventilatory response were measures. JS

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE