Accession Number:

ADA229063

Title:

Receptor Binding and Membrane Transport of Botulinum Toxins

Descriptive Note:

Annual rept. 1 Apr 1988-31 Mar 1989,

Corporate Author:

FLORIDA UNIV GAINESVILLE COLL OF VETERINARY MEDICINE

Personal Author(s):

Report Date:

1989-03-01

Pagination or Media Count:

12.0

Abstract:

The goal of this research is to characterize the interaction of the botulinum type neurotoxins with target membranes and seeks to add to the field of study of toxincell interactions. Also, this research project seeks to determine any similarity between the mechanism of action of botulinum toxins and a number of other protein toxins whose mechanism of action has been more clearly defined. Through the utilization of antibodies to a series of diverse protein toxins and an artificial liposome target system for the botulinum toxin, it is hoped that the mechanism of action of the toxin can be better defined. Also, this will allow us to gain an understanding of how to inhibit the action of this toxin. JS

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE