Structure and Expression of Genes for Flavivirus Immunogens
Annual summary rept. 15 Jun 1988-14 Jun 1989
MASSACHUSETTS UNIV AMHERST DEPT OF BIOCHEMISTRY
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Progress during the reporting period included i expression of a DEN- virus neutralizing epitope in E. coli ii expression of DEN- structural proteins and 80 of the NS protein by a recombinant baculovirus iii extension of the DEN- sequence into the NS5 coding region and iv development of an assay to detect DEN- RNA by non-radioactive means. Keywords DNA probes Recombinant DNA, Flaviviruses Subunit vaccine Diagnosis Mice Gene mapping Biotechnology BW cDNA Cloning Dengue fever.
- Medicine and Medical Research