Accession Number:

ADA224742

Title:

Structure and Expression of Genes for Flavivirus Immunogens

Descriptive Note:

Annual summary rept. 15 Jun 1988-14 Jun 1989

Corporate Author:

MASSACHUSETTS UNIV AMHERST DEPT OF BIOCHEMISTRY

Report Date:

1990-06-28

Pagination or Media Count:

8.0

Abstract:

Progress during the reporting period included i expression of a DEN- virus neutralizing epitope in E. coli ii expression of DEN- structural proteins and 80 of the NS protein by a recombinant baculovirus iii extension of the DEN- sequence into the NS5 coding region and iv development of an assay to detect DEN- RNA by non-radioactive means. Keywords DNA probes Recombinant DNA, Flaviviruses Subunit vaccine Diagnosis Mice Gene mapping Biotechnology BW cDNA Cloning Dengue fever.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE