Accession Number:

ADA224732

Title:

Development of Serologic Assays for the Diagnosis of New World Leishmaniasis

Descriptive Note:

Annual rept. 1 Dec 1983-30 Nov 1984

Corporate Author:

MARYLAND UNIV BALTIMORE SCHOOL OF MEDICINE

Personal Author(s):

Report Date:

1985-02-01

Pagination or Media Count:

31.0

Abstract:

Genus specific monoclonal antibodies have been generated to 14 different isolates of New World Leishmania. These antibodies have been used to identify closely related subspecies to recover genus-specific antigens for the development of sero-diagnostic assays and to identify parasites in infected tissues to quantitate antigen expression on the surface membrane by flow cytometry. Keywords Leishmania Monoclonal antibodies Amastigotes Serodiagnosis Flow cytometry Immunopathology.

Subject Categories:

  • Medicine and Medical Research
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE