Accession Number:

ADA224731

Title:

Development of Serologic Assays for the Diagnosis of New World Leishmaniasis

Descriptive Note:

Annual rept. 1 Dec 1984-30 Nov 1985

Corporate Author:

MARYLAND UNIV BALTIMORE SCHOOL OF MEDICINE

Personal Author(s):

• Anthony, Ronald L.

Report Date:

1986-02-20

Pagination or Media Count:

208.0

Abstract:

Monoclonal antibodies, generated against the New World Leishmania have been used to identify taxons, dissect complex antigenic profiles, study host cell-parasite interactions, detect parasites in tissues of the host, develop species-specific serodiagnostic assays and to study the immunopathology of the disease. Keywords Leishmania Trypanosomes Monoclonal antibodies Specific antigens Serodiagnosis Immunopathology.

Descriptors:

• *LEISHMANIA
• *ANTIGENS
• *SERODIAGNOSIS
• *LEISHMANIASIS
• MONOCLONAL ANTIBODIES
• PARASITES
• IMMUNITY
• SEROLOGY
• TAXONOMY
• HOSTS(BIOLOGY)
• BIOASSAY
• PATHOLOGY
• PROFILES
• TRYPANOSOMA
• TISSUES(BIOLOGY)
• INTERACTIONS

Subject Categories:

• Biochemistry
• Medicine and Medical Research
• Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE