Accession Number:

ADA224495

Title:

Comparative Aspects of Host-Parasite and Host-Tumor Relationships

Descriptive Note:

Final rept.

Corporate Author:

ROSWELL PARK MEMORIAL INST BUFFALO NY

Personal Author(s):

Report Date:

1989-11-16

Pagination or Media Count:

4.0

Abstract:

The first session of the conference on Interleukin 1, was chaired by Dr. Oppenheim. The discussion dealt initially with the induction of IL-1 by several cell types, and maybe most interesting, induction by injury. Because IL- 1 alpha is released more slowly than IL-1 Beta, it was suggested that beta is the intercellular signal and alpha may accelerate subsequent cell mediated reactions. Because IL-1 augments the actions of many cell types in the immune system including antibody production and also the production of other lymphokines, IL-1 has promising therapeutic potential. Dr. Wallach reported that IL-1 prevents bacterial shock by inhibiting the effects of TNF. JES

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE