Accession Number:

ADA224381

Title:

A Circuit Analysis and Computational Model of Operant Conditioning in Aplysia

Descriptive Note:

Annual technical rept. 1 Jul 1989-30 Jun 1990

Corporate Author:

YALE UNIV NEW HAVEN CT

Personal Author(s):

Report Date:

1990-06-19

Pagination or Media Count:

5.0

Abstract:

Our primary objective is to carry out a cellular and computational analysis of operant conditioning of the headwaving response in Aplysia. Progress has been made in four areas 1 We have now unequivocally identified the neural pathway essential for reinforcement a bilateral set of nerves from the oral veil. 2 We have achieved reliable stimulus control over the operant response headwaving by our discovery that Aplysia shows a strong positive phototaxis to a directional light source. 3 We have identified the neural pathway necessary for phototaxis the nerves from the primary visual organs the eyes and rhinophores. 4 We have preliminary evidence that headwaving motor neurons can be operantly conditioned by direct injection of hyperpolarizing or depolarizing current, paired with reinforcement to increase or decrease their spontaneous firing rate.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE