Accession Number:

ADA222730

Title:

Dengue Fever in American Military Personnel in the Philippines: Clinical Observations on Hospitalized Patients during a 1984 Epidemic

Descriptive Note:

Technical rept. Jun-Aug 1984

Corporate Author:

NAVAL MEDICAL RESEARCH UNIT NO 2 DETACHMENT JAKARTA (INDONESIA)

Report Date:

1989-03-01

Pagination or Media Count:

11.0

Abstract:

From June-Aug 1984, 24 American military personnel were hospitalized with dengue DEN at Clark Air Base in the Philippines. Their infections were confirmed by serology using the hemagglutination-inhibition test andor by virus isolation in Aedes pseudoscutellaris cell cultures. Most of the patients had a secondary type of antibody response probably reflecting prior vaccination against yellow fever. Three serotypes of DEN virus were isolated 7 isolates of DEN 1, 4 isolates of DEN 3 and 3 isolates of DEN 2. All of the patients were Caucasian males between the ages of 20-43 years. All of the cases were clinically diagnosed as classical dengue fever. A platelet count 100,000ul was a common finding 83.3 however, hemoconcentration was not documented. Other major findings were the occurrence of mild hypotension 62.5 and petechiae 37.5. One patient presented with shock and upper gastrointestinal bleeding, but his diagnosis was complicated by a history of epigastric pain and use of aspirin. Although all of the patients fully recovered, the severity of illness was clearly documented by the average-length of hospitalization 5.9 days and average time absent from work 8.7 days. Keywords Dengue fever, Clark air base, 1984 dengue epidemic, Philippines.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE