Accession Number:

ADA218937

Title:

Laser Retinal Effects: Electrophysiological Determination in Visual Cortical Cells of Monkeys and Cats

Descriptive Note:

Final rept. 1 Apr 1987-31 Aug 1988,

Corporate Author:

SACKLER SCHOOL OF MEDICINE TEL AVIV (ISRAEL)

Personal Author(s):

Report Date:

1989-06-25

Pagination or Media Count:

28.0

Abstract:

The purpose of the present study was to examine electrophysiologically the effect of laser induced retinal lesions on the visual cortex of mammalian animal model. The effect of threshold energy levels of laser radiation was studied acutely and chronically in cats using the visual evoked response VER. In addition, electroretinographic ERG studies have been added to the program to obtain direct physiological evidence on the condition of the retinal area affected by the laser radiation. This study was coordinated with LAIR personnel the P.I. visited two times in LAIR, especially with regard to the type of laser technology to be used and its availability in the Goldschleger Eye Institute. A Neodymium YAG laser device NdYAG was used energy levels applied were 0.1-1.0 millijoules mJ and 1-100 pulses were given to the various cats. The results showed that the ERG is affected the lased eye was less excitable than the normal eye in most of the cats studied, whatever laser energy has been applied. The findings of the visual evoked response VER showed that in most cats the lased eye was inferior to the normal eye. An effect was found even in cases where energy level was as small as 0.1 mJ and whether the animals were exposed to the laser radiation 1 day or 6 weeks prior to the recording session. sdw

Subject Categories:

  • Anatomy and Physiology
  • Lasers and Masers

Distribution Statement:

APPROVED FOR PUBLIC RELEASE