Accession Number:

ADA218412

Title:

Role of Protein Methylation in Halobacterium halobium Phototaxis

Descriptive Note:

Annual rept. 1 Feb 1989-31 Jan 1990

Corporate Author:

ALBERT EINSTEIN COLL OF MEDICINE OF (YESHIVA UNIV) BRONX NY

Personal Author(s):

Report Date:

1990-02-01

Pagination or Media Count:

5.0

Abstract:

This project is part of an effort to understand the physical chemical basis of sensory and energy transduction by biological membranes using a model system the bacterial rhodopsins of the archaebacterium H. halobium. Our objective is to gain insight into the mechanism of signaling by the phototaxis receptors sensory rhodopsin I and II SR-I and SR-II. Methylation of a set of integral membrane proteins is required for taxis adaption in H. halobium and a 94 kd protein has been linked specifically to SR-I. We aim to determine the relationship between this protein and the 25 kd chromophoric polypeptide of SR- I, and the role of methylation in modulation of phototaxis signals. Keywords Biosensors Biochemistry.

Subject Categories:

  • Biochemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE