Hemorrhagic Fever with Renal Syndrome (Korean Hemorrhagic Fever)
Annual summary rept. 10 Feb 1988-9 Feb 1989
KOREA UNIV SEOUL COLL OF MEDICINE
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Hantavirus is ubiquitous in the world and the total number of reported HFRS patient in Euro-Asia is about 200,000 with 5-7 mortality annually. Hemorrhagic fever with renal syndrome HFRS is an important military problem since large epidemics of HFRS occurred among soldiers in many past wars and although predominantly associated with field mice in rural areas, it is now being recognized that urban rats and laboratory rats are also reservoirs of HFRS in many parts of the world. Therefore, global surveys of the distribution of hantaviruses and surveillance of HFRS are important for prevention of this highly fatal disease. It is also important to investigate antigenic differences of strains of Hantavirus isolated from rodents caught in non-endemic areas of the world because HFRS patients have never been documented in many areas despite the finding of positive rodents there. Keywords Hantavirus Hantaan virus Seoul virus Puumala virus Scrub typhus Murine typhus Spotted fever Seroepidemiology IFA Elisa PRNT RA I.
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