Accession Number:

ADA214263

Title:

Dermal Sensitization Potential of Nitrosoguanidine in Guinea Pigs

Descriptive Note:

Institute rept. 30 Jan-14 Mar 1986

Corporate Author:

LETTERMAN ARMY INST OF RESEARCH PRESIDIO OF SAN FRANCISCO CA

Report Date:

1989-09-01

Pagination or Media Count:

42.0

Abstract:

Nitrosoguanidine was evaluated for its potential to produce dermal sensitization in male guinea pigs. The Buehler test, which utilizes repeated closed patch inductions with the test compound, was used for this evaluation. No evidence of nitrosoguanidine-induced sensitization was obtained in the study. Keywords Triple base propellants Dermal sensitization Nitrosoguanidine Mammalian toxicology Guinea pigs Buehler test Nitroguanidine. kt

Subject Categories:

  • Toxicology
  • Ammunition and Explosives

Distribution Statement:

APPROVED FOR PUBLIC RELEASE