Accession Number:

ADA210685

Title:

Excitatory Amino Acids as Transmitters in the Brain

Descriptive Note:

Final rept. 1 May 1986-30 Apr 1989

Corporate Author:

CALIFORNIA UNIV IRVINE

Personal Author(s):

• Cotman, C. W.

Report Date:

1989-04-30

Pagination or Media Count:

12.0

Abstract:

The overall goal of this work was to carry out an indepth study of the properties of the excitatory amino acid neurotransmitter receptors. These receptor represent an integral part of the central nervous system, as they are responsible for the majority of the excitatory synaptic transmission, as well as being involved in higher order processes such as plasticity and excitotoxicity. Considerable advances have been made in our understanding of these receptors. The results of these studies are summarized below with respect to each of the receptor classes.

Descriptors:

• *NEUROCHEMISTRY
• *AMINO ACIDS
• *NERVE TRANSMISSION
• CHEMISTRY
• PLASTIC PROPERTIES
• SENSE ORGANS
• NEUROLOGY
• BRAIN
• CENTRAL NERVOUS SYSTEM
• TRANSMITTANCE
• SITES
• SYNAPSE

Subject Categories:

• Biochemistry
• Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE