Accession Number:

ADA210068

Title:

Experimental Treatment of Burn Victims in Field Hospitals

Descriptive Note:

Corporate Author:

MASSACHUSETTS INST OF TECH CAMBRIDGE

Personal Author(s):

Report Date:

1989-05-12

Pagination or Media Count:

29.0

Abstract:

A method for separating the Langerhans cell population from a mixed dermal and epidermal cell population was studied. The long term objective of this research is the design of skin grafts which are donor-independent. This research is based on the hypothesis that the Langerhans cells in the skin are the most significant contributors to the phenomenon of skin graft rejections. Several methods were considered before designing a monolayer panning technique. The panning technique, based on the highly specific affinity of the monoclonal antibody OKT-6, proved to be very effective in achieving a cell separation. Keywords Skin anatomy Grafting Burns injuries Field hospitals Therapy RA2.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE