Cloning of Plasmodium yoelii Genes Expressing Three Different Sporozoite-Specific Antigens
NAVAL MEDICAL RESEARCH INST BETHESDA MD
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Despite the rapid advances in the development of a recombinant vaccine against Plasmodium falciparum sporozoites, there is still an urgent need for a reliable rodent model to carry out complex vaccine protocols difficult to perform in primates or man. The purpose of this research was to clone the P. yoelii genes coding for sporozoite antigens that have potential as vaccine candidates in a rodent model. Keywords Sporozoite antigens Plasmodium yoelii Recombinant DNA Monoclonal antibodies Rodent malaria Reprints.
- Genetic Engineering and Molecular Biology
- Medicine and Medical Research