IV (Intravenous) Fluidmaker: Preparation of Sterile Water for Injection in a Field Setting
Technical rept. 25 Apr-29 Oct 1988
ARMY BIOMEDICAL RESEARCH AND DEVELOPMENT LAB FORT DETRICK MD
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Two small, hand-operated systems have been devised for generating sterile, pyrogen-free water for injection WFI in the field. Both systems utilize reverse osmosis, ion exchange, a solid matrix filter containing activated carbon and zeta adsorbent, a final 0.2 micron pore-size sterilizing filter and a device for transferring the WFI to an IV bag. Both systems are capable of producing WFI according to U.S. Pharmacopeia XXI standards. The smaller system weighs approximately 3.5 kg and produces 1 liter of WFI in 5-6 minutes. Parenteral solutions were made by adding WFI to an IV bag containing concentrated Ringers lactate.
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