Accession Number:

ADA200148

Title:

Hemorrhagic Fever with Renal Syndrome (Korean Hemorrhagic Fever)

Descriptive Note:

Annual summary rept. 10 Feb 1987-9 Feb 1988

Corporate Author:

KOREA UNIV SEOUL COLL OF MEDICINE

Personal Author(s):

Report Date:

1988-06-30

Pagination or Media Count:

56.0

Abstract:

There were 701 cases of hospitalized Hemorrhagic Fever with Renal Syndrome HFRS patients serologically confirmed at our laboratory and, 163 and 5 of them were ROK Army and US Army soldiers, respectively in Korea, 1987. Epidemic of scrub typhus occurred about a month before the peak of HFRS and 209 scrub typhus patients were diagnosed at out laboratory among 1,530 suspect HFRS in 1987. Serologic survey of infected wild Apodemus agrarius with Hantaan virus, R. tsutsugamushi and Leptospira interogans in the U.S. Marine and ROK Army camps in Wucheon, Kyunggido showed higher infection rate of mice with the agents in the US Marine camp than ROK Army camp. A new serotype of Hantavirus was identified and 4 strains of Hantaan virus were isolated from Apodemus agrarius caught in Jinhae, Kyungsangnamdo, Korea where HFRS were not reported previously. As a part of global survey of HFRS, Hantavirus Infection was demonstrated for the first time not only among laboratory personnel but also in experimental rats and wild mice, C. musculinus in Argentina. A strain of Seoul virus was isolated from a Syrian hamster purchased from a local animal farm. In our limited study, inbred hamsters were broad spectrum animals to support multiplication of hantaviruses and 2 out of 4 inbred hamsters PD4 died about 20 days after inoculation of a strain of Hantaan virus. Keywords Puumala virus, Maaji virus, Seroepidemiology, Immunoassay.

Subject Categories:

  • Medicine and Medical Research
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE