Accession Number:

ADA200129

Title:

A Core Facility for the Study of Neurotoxins of Biological Origin

Descriptive Note:

Annual rept. 15 May 1986-14 May 1987

Corporate Author:

JEFFERSON MEDICAL COLL PHILADELPHIA PADEPT OF MEDICINE

Personal Author(s):

Report Date:

1987-06-15

Pagination or Media Count:

64.0

Abstract:

Research has been conducted in three thematic areas, as follows Neurological studies, Neuropharmacological and immunological studies, Electrophysiological studies, The data that have been obtained fall into six major categories i. Definitive studies on the central nervous system effects of tetanus toxin, ii. Initial studies on the isolation and characterization of gyroxin, iii. Concluding studies on the enzymatic properties of the botulinum binary toxin, iv. Continuing studies on the development of a secretory cell that is responsive to most or all of the neurotoxins of interest, V. Concluding studies on deltamethrin and sodium channels in nerve cells grown in culture, vi. Continuing studies on ryanodine and calcium flux in excitable tissues.

Subject Categories:

  • Toxicology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE