Accession Number:

ADA199381

Title:

Primary Dermal Irritation Potential of Trimethylolethane Trinitrate (TMETN) in Rabbits

Descriptive Note:

Final rept. 24 Oct-13 Nov 1984

Corporate Author:

LETTERMAN ARMY INST OF RESEARCH PRESIDIO OF SAN FRANCISCO CA

Personal Author(s):

Report Date:

1986-10-01

Pagination or Media Count:

23.0

Abstract:

The primary dermal irritation potential of trimethylolethane trinitrate TMETN was determined in male and female New Zealand White rabbits using a modified Draize method. The test compound was non-irritating. Very slight erythema was observed in 2 rabbits by 12 hour after dosing and in 4 rabbits at 24 hours after dosing. All rabbits had returned to normal by 48 hours after dosing. Neither edema nor any other recognizable skin reaction was detected at any time during the 14-day observation period. Keywords Primary dermal irritation, Trimethylolethane trinitrate, TMETN, Mammalian toxicology, Rabbits, Munitions.

Subject Categories:

  • Toxicology
  • Nuclear Weapons

Distribution Statement:

APPROVED FOR PUBLIC RELEASE