Accession Number:

ADA199154

Title:

Mutagenic Potential of Nitrosoguanidine in the Drosophila melanogaster Sex-Linked Recessive Lethal Test

Descriptive Note:

Final rept.

Corporate Author:

LETTERMAN ARMY INST OF RESEARCH PRESIDIO OF SAN FRANCISCO CA

Report Date:

1988-08-01

Pagination or Media Count:

27.0

Abstract:

Nitrosoguanidine, an anticipated degradation product of nitroguanidine which in turn is a primary component of U.S. Army tripe-base propellants, was evaluated for mutagenic potential in the Drosophila melanogaster Sex-Linked Recessive Lethal test. Nitrosoguanidine was non- mutagenic following 72-hour feeding exposures to concentrations of nitrosoguanidine ranging from 5 mgml to 50 mgml. Keywords Mutagenicity, Genetic toxicology.

Subject Categories:

  • Toxicology
  • Ammunition and Explosives

Distribution Statement:

APPROVED FOR PUBLIC RELEASE