Accession Number:

ADA197053

Title:

Three-Dimensional Computer Graphics Brain-Mapping Project

Descriptive Note:

Final rept. 10 Mar-24 Dec 1987

Corporate Author:

CALIFORNIA UNIV SAN DIEGO LA JOLLA

Personal Author(s):

Report Date:

1988-03-24

Pagination or Media Count:

144.0

Abstract:

We assembled a core group at UCSD and the Scripps Clinic and Research Foundation, which, together with participating national advisors, could solve problems that stand in the way of engaging computer graphics and database management more effectively in the solution of neurosciences problems. We aimed at improving the interface between neuroanatomy and computer graphics systems so that the groundwork for accurate quantitative morphology will be satisfactory from the neurosciences viewpoint in proceeding to achieve whole brain reconstructions. We have succeeded in developing sound methods for preparing whole brains for sectioning and microscopic analysis, with controls for reducing brain distortions in three dimensions and for correcting the inevitable distortions that accompany slicing brain tissue at microscopic intervals, for combining structurefunction data, and for beginning an analysis of whole brain tissue sections at microscopic levels of detail. Keywords Brain mapping, Neuroanatomy, Computer graphics, Image processing, Data bases, Anatomical models.

Subject Categories:

  • Anatomy and Physiology
  • Computer Programming and Software

Distribution Statement:

APPROVED FOR PUBLIC RELEASE