Accession Number:

ADA193111

Title:

A Spectroscopy of Helix Melting.

Descriptive Note:

Annual progress rept. Apr 87-Mar 88,

Corporate Author:

PURDUE RESEARCH FOUNDATION LAFAYETTE IN

Personal Author(s):

• Prohofsky, Earl W.

Report Date:

1987-03-11

Pagination or Media Count:

3.0

Abstract:

We have calculated the far infrared absorption for several models of double helical DNA. These results are in good agreement with experimental observations. We have also fitted our results to observed inelastic neutron scattering data. Again the results are in excellent agreement with observation. We have extended our calculations on helix strand melting to include methylated DNA and many other DNAs of varying base pair sequence. All of the results are useful in leading to more precise predictions of the dynamics of DNA strand separation in a far infrared radiation field. We have also extended our model so as to predict energy flow in the natural process of RNA transcription. Keywords Helix melting, Deoxyribonucleic acid, Free electron laser irradiation.

Descriptors:

• *DEOXYRIBONUCLEIC ACIDS
• *HELIXES
• *ABSORPTION SPECTRA
• *RADIATION EFFECTS
• DYNAMICS
• ELECTRON IRRADIATION
• ENERGY TRANSFER
• FAR FIELD
• FAR INFRARED RADIATION
• FREE ELECTRON LASERS
• INELASTIC SCATTERING
• MELTING
• METHYLATION
• NEUTRON SCATTERING
• PRECISION
• RIBONUCLEIC ACIDS
• SPECTROSCOPY
• STRANDS
• GENETICS

Subject Categories:

• Radiobiology
• Genetic Engineering and Molecular Biology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE