Experimental Third Degree Frostbite in Hanford Miniature Swine
ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
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Third degree frostbite was produced in five Hanford Miniature Swine exposed to chilled air. Biopsies were taken. The 200 slides were evaluated microscopically epithelial necrosis and regeneration were recorded as absent or present. Vascular degeneration, thrombosis, sweat gland injury, and subcutis injury were ranked. Epithelial necrosis andor regeneration were seen consistently, but not until 1-2 weeks after injury. Vascular injury was absent for the 1 minute freeze, but was seen by 48 hours for the 5, 10, and 20 minute freezes. Sweat gland injury was seen by 12 hours for all freezes except the 1 minute freeze. Subcutis changes were seen 1-2 weeks after injury.
- Medicine and Medical Research
- Stress Physiology