Accession Number:

ADA181931

Title:

Effect of Temperature on the Vector Efficiency of Aedes aegypti for Dengue 2 Virus

Descriptive Note:

Journal articlce.

Corporate Author:

ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD

Report Date:

1986-06-26

Pagination or Media Count:

10.0

Abstract:

The effect of temperature on the ability of Aedes Aegypti to transmit dengue DEN 2 virus to rhesus monkeys was assessed as a possible explanation for the seasonal variation in the incidence of dengue hemorrhagic fever in Bangkok, Thailand. In two laboratory experiments, a Bangkok strain of Ae. aegypti was allowed for feed upon viremic monkeys infected with DEN-2 virus. Blood-engorged mosquitoes were separated into two groups and retained at constant temperatures. Virus infection and transmission rates were determined for Ae. aegypti at intervals ranging from 4 to 7 days during a 25-day incubation period. Results of the first experiment for mosquitoes infected with a low dose of DEN-2 virus and maintained at 20, 24, 26, and 30C, indicated that the infection rate ranged from 25 to 75 depending on the incubation period. However, DEN-2 virus was transmitted to monkeys only by Ae. aegypti retained at 30C for 25 days. In the second experiment, the infection rate for Ae. aegypti that ingested a high viral dose, and incubated at 26, 30, 32, and 35C ranged from 67 to 95. DEN-2 virus was transmitted to monkeys only by mosquitoes maintained at or 30C. The extrinsic incubation period was 12 days for mosquitoes at 30C, and was reduced to 7 days for mosquitoes at 32C and 35C. These results imply that temperature-induced variations in the vector efficiency of Ae. aegypti may be a significant determinant in the annual cyclic pattern of dengue hemorrhagic fever epidemics in Bangkok.

Subject Categories:

  • Medicine and Medical Research
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE