Accession Number:

ADA175666

Title:

Effects of Infection on Oxygen Consumption and Core Temperature in Experimental Thermal Injury

Descriptive Note:

Corporate Author:

ARMY INST OF SURGICAL RESEARCH FORT SAMHOUSTON TX

Report Date:

1986-07-01

Pagination or Media Count:

5.0

Abstract:

Oxygen consumption VO2 and colonic temperature T sub C measured in groups of rats before and after 30 total body surface, full thickness burns. Some wounds were seeded with Pseudomonas aeruginosa or Staphylococcus epidermidis, and some seeded wounds were treated with SULFAMYLON or SILVADENE. Three groups became bacteremic B during the 2-3 week period of observation. The metabolic cost of wound contamination appeared to vary with bacterial strain. The metabolic effects of infection appeared to vary with bacterial strain. The metabolic effects of infection appear to be a continuum, beginning with a modest rise in VO2 and progressing to greater increases in VO2 and T sub C with wound invasion and systemic infection.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE