Geometric Universality in Brain Allosteric Protein Dynamics: Complex Hydrophobic Transformation Predicts Mutual Recognition by Polypeptides and Proteins,
CALIFORNIA UNIV SAN DIEGO LA JOLLA DEPT OF PSYCHIATRY
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A relationship is derived between the thermodynamic entropy-enthalpy compensation of proteins and hyperbolic dynamics of their resting, signal-sensitive behavior. This formulation is then used to derive a hydrophobic sequence code which successfully predicts structure and function in a variety of polypeptide hormones.
- Atomic and Molecular Physics and Spectroscopy