Study of the Pathogenicity of Aeromonas hydrophila for Man
Annual rept. 1 Sep 1984-30 Nov 1985
TEXAS UNIV HEALTH SCIENCE CENTER AT HOUSTON
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Five Aeromonas hydrophila strains were selected for study from among more than 50 candidate strains collected from Thailand, Western Australia, Canada, and the United States. They were selected for the study because of possession of well characterized virulence properties or because they were clearly implicated in cases of human diarrheal illness. All were felt to be pathogenic by laboratory assays. The strains were tested biochemically and toxin production and hemagglutination patterns were characterized. Each strain was then fed to groups of 3 or 4 adult volunteers. The strains were shed by the volunteers only sporadically and except for two volunteers transently passing unformed stools, a sustained illness did not develop. This study failed to show a relationship between virulence properties as we now understand them and pathogenicity of Aermonas for human subjects.
- Medicine and Medical Research