Chemical Preparation Laboratory IND Candidate Compounds.
Annual rept. 17 Jan 85-16 Jan 86,
PHARM-ECO LABS INC SIMI VALLEY CA
Pagination or Media Count:
Six compounds were synthesized during the reporting period 3-Beta-D-ribofuranoxyl-1Hpyrazolo4,3-Dpyrimidin-76Hthione Thioformycin-B 9-Beta-D-ribofuranoxyl-purine-6-thiocarboxamide 3-bromo-4-chloro-pyrazolo 3.4-dpyrimidine 2-Beta-D-ribofuranosylselenazo-4-caboxamide cis, trans 3,6-diethoxy-tetrazadiphosphorine-3,6-disulfide 1-Beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide Ribavirin. The syntheses of ten target compounds have been examined during this annual period. The preparations of six of the ten target compounds were completed, and the compounds were transferred to USAMRIID, Department of Antiviral Studies. The syntheses of the four remaining target compounds, three of which are unreported in the chemical literature, are being further investigated.
- Organic Chemistry