Accession Number:

ADA172191

Title:

The Use of Hypertonic Solutions to Resuscitate Animals from Hypovolemic Shock.

Descriptive Note:

Annual rept. 1 Jul 83-30 Jun 84,

Corporate Author:

CALIFORNIA UNIV DAVIS SCHOOL OF MEDICINE

Personal Author(s):

• Holcroft,James W.
• Kramer,George
• Green,Jerry F.

Report Date:

1984-08-01

Pagination or Media Count:

48.0

Abstract:

This report pertains to the use of hypertonic solutions to resuscitate animals from hypovolemic shock. In brief, it appears that a solution comprised of sodium chloride, with a calculated osmolality of 2,400 milliosmolskg mixed with a dextran solution, provides good resuscitation from hemorrhagic shock in sheep. This resuscitation is longer lasting than resuscitation with equivalent volumes of normal saline. The resuscitation also seems better than when using solutions containing sodium acetate, mannitol, glucose, or sodium bicarbonate.

Descriptors:

• *SALINE SOLUTION
• *TRAUMATIC SHOCK
• *RESUSCITATION
• VOLUME
• DEXTRAN
• SODIUM
• SOLUTIONS(GENERAL)
• WOUNDS AND INJURIES
• SODIUM CHLORIDE
• ACETATES
• GLUCOSE
• HEMORRHAGIC SHOCK
• SHEEP
• BICARBONATES
• SODIUM COMPOUNDS
• HYPERTONIC
• MANNITOL

Subject Categories:

• Biology
• Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE