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The Use of Hypertonic Solutions to Resuscitate Animals from Hypovolemic Shock.
Annual rept. 1 Jul 83-30 Jun 84,
CALIFORNIA UNIV DAVIS SCHOOL OF MEDICINE
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This report pertains to the use of hypertonic solutions to resuscitate animals from hypovolemic shock. In brief, it appears that a solution comprised of sodium chloride, with a calculated osmolality of 2,400 milliosmolskg mixed with a dextran solution, provides good resuscitation from hemorrhagic shock in sheep. This resuscitation is longer lasting than resuscitation with equivalent volumes of normal saline. The resuscitation also seems better than when using solutions containing sodium acetate, mannitol, glucose, or sodium bicarbonate.
APPROVED FOR PUBLIC RELEASE