Accession Number:

ADA171645

Title:

Fundamental Studies in the Molecular Basis of Laser Induced Retinal Damage.

Descriptive Note:

Annual rept. Feb-Sep 81,

Corporate Author:

CORNELL UNIV ITHACA NY

Personal Author(s):

Report Date:

1981-09-01

Pagination or Media Count:

21.0

Abstract:

Laser spectroscopy experiments have focused on cones in the red-eared swamp turtle, Pseudemys scripta elegans. Our choice of this system was based on the desire to correlate our molecular data with the extensive data being collected on this system by Dr. Zwick in his studies on laser hazards at LAIR. Thus, a detailed collaborative effort was initiated on this system during the past year. The experiments have already resulted in important information which opens new avenues to explore fundamental molecular mechanisms of retinal damage with laser irradiation. Results of these experiments will be summarized in the following sections I. Elucidation of the role of oil droplets in the absorption of light by the turtle retina II. A Selective Probe of Membrane Potentials in Turtle Cone Cells III. Angstrom Resolution Light Microscopy of Photoreceptor Cells IV. Identification and Selective Staining of Other Important Molecular Components of Photoreceptor Cells.

Subject Categories:

  • Biochemistry
  • Radiobiology
  • Lasers and Masers

Distribution Statement:

APPROVED FOR PUBLIC RELEASE