Accession Number:

ADA170737

Title:

Rapid Diagnosis of Arbovirus and Arenavirus Infections by Immunofluorescence.

Descriptive Note:

Annual progress rept. 1 Feb 82-31 Jan 83,

Corporate Author:

YALE UNIV NEW HAVEN CONN SCHOOL OF MEDICINE

Personal Author(s):

Report Date:

1983-01-31

Pagination or Media Count:

18.0

Abstract:

A serologic survey of equatorial Africa for antibodies in man to Crimean- hemorrhagic fever-Cong, Rift Valley fever, Ebola, Lassa fever, and Marburg viruses was continued. In Sudan, prevalence rates were Marburg 0.2, CCHF 0.7, Lassa 3.9, RVF 4.6, EBO-Zaire 8.2, and EBO-Sudan 11.2. Significant geographic clustering of antibody positive sera occurred for Lassa, EBO-Z and EBO-S viruses. Over 1000 sera from the Benue river basin in Nigeria which were collected by WHO in 1964-1965 have been tested. The prevalence rates are Congo 27, RVF 17, EBO-Z 6, EBO-S 39 with 27 positive to Congo, and 29 positive to Lassa. An ELISA for CCHF virus has been developed. Human sera from Ethiopia and Senegal are still under study. From preliminary results, it appears that the rate of positive reactions varies with geographic region within each country.

Subject Categories:

  • Medicine and Medical Research
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE