Accession Number:

ADA169506

Title:

Water Quality Criteria for Hexahydro-1,3,5-Trinitro-1,3,5-Triazine (RDX)

Descriptive Note:

Final rept.

Corporate Author:

OAK RIDGE NATIONAL LAB TN

Personal Author(s):

Report Date:

1986-06-01

Pagination or Media Count:

119.0

Abstract:

Health and environmental effects data were analyzeed for RDX and a literature review presented. Information on the toxic effects of RDX on aquatic organisms is limited. From the data that are available, it appears that freshwater fish are more susceptible to RDX toxicity than freshwater invertebrates, having a range of LC50 values from 4.1 to 6.0 mgL in 96-hr static tests, and 6.6 to 13 mgL in 96-hr flow-through tests. EC50 values based on immobilization of 15 mgL in flow-through tests and 100 mgL in static tests were reported for four freshwater invertebrate species. Bioconcentration of RDX in freshwater fish appears to be minimal, with values for edible tissue ranging from 1.4 to 1.7. Chronic RDX intoxication in workers is characterized by epileptiform seizures generalized convulsions and unconsciousness. Seizures are followed by temporary amnesia, disorientation, and asthenia. No clinical information describing fatal cases of RDX poisoning is available. Oral LD50 values reported in the literature for RDX range from 44 to 300 mgkg in the rat. During a 2-yr feeding study with rats, the major toxic effects of RDX included anemia with secondary splenic lesions, hepatotoxicity, possible CNS involvement, and urogenital lesions. Insufficient data were available to calculate a water quality criterion for aquatic organisms using USEPA guidelines. Based on noncarcinogenic mammalian toxicity data, an ambient water quality criterion for the protection of human health and sensitive populations of 103 microgramsL is proposed.

Subject Categories:

  • Toxicology
  • Civil Engineering
  • Ammunition and Explosives

Distribution Statement:

APPROVED FOR PUBLIC RELEASE