Accession Number:

ADA167079

Title:

Neuronal Basis of Learning.

Descriptive Note:

Final rept. 10 Oct 83-1 Sep 86,

Corporate Author:

OREGON STATE UNIV CORVALLIS

Personal Author(s):

Report Date:

1986-03-03

Pagination or Media Count:

9.0

Abstract:

Our studies on the relatively simple nervous systems of the molluscs Pleurobranchaea and Aplysia have inquired into the neuronal basis of integrated behavior, the effect of learning on such integration, identification of neurons involved in the learned behavior, and small network modeling of learning. Significant findings are 1 Neurocircuits establishing whole-animal behavior functionally emerge or self-organize within pools of coactive neurons i.e., functional neurocircuits arise moreso from nonlinear dynamical properties than from static switchboard anatomical ones. 2 Pharmacologic antagonists of cholinergic muscarinic receptors enhance one-trial Pavlovian conditioning. The specificity of this effect on associative processes provides an important inroad for experiments aiming to identify neurons involved in learning, and also to understand how learning biases self-organization. 3 In support of a goal-seeking theory of learning, conditioning of small nerve networks shows that cellular changes relating to an analog of learning involve postsynaptic processes in addition to presynaptic ones. These findings have broad implications in neurosciences and artificial intelligence. Keywords Associative learning, Parallel processing, Self-organization, Pavlovian conditioning, Muscarinic receptors, Cholinergic Identified neurons, Distributed function, Nerve nets.

Subject Categories:

  • Psychology
  • Anatomy and Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE