Accession Number:

ADA165015

Title:

Urinary and Hematological Indices of Hypohydration,

Descriptive Note:

Corporate Author:

ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA

Report Date:

1986-01-01

Pagination or Media Count:

22.0

Abstract:

As part of a large scale field feeding system test we had the unique opportunity to collect and study hundreds of overnight urine aliquots which were obtained immediately prior to a fasting blood sample on days 1, 20, and 44 of the field test. To evaluate the hydrational status of test subjects and criteria of hypohydration, urine aliquots were categorized by specific gravity or 1.03 n124 or 1.03 n540. Creatinine levels were elevated p.001 in the concentrated urine samples, but a decreased trend in NaK ratios in these samples failed to achieve statistical significance p0.1. However, when individuals with high specific gravity urine were further subclassified by a criterion of weight loss 3 from original body weight, then creatinine concentrations were elevated p.05 while NaK ratios were decreased p.05 when compared with levels in subjects also with high specific gravity but weight loss 3. Serum urea nitrogencreatinine ratios were significantly increased days 1 and 44, p.02 in test subjects whose urine samples exceeded 1.03 in specific gravity. The results of this study indicated that prodromal hypohydration, indicated by concomitant elevations in urinary specific gravity and creatinine, was not reflected in the common indices of circulatory hypohydration- hematocrit and osmolality. Alternatively, urea nitrogencreatinine ratio may be a sensitive circulatory index of imminent hypohydration.

Subject Categories:

  • Biochemistry
  • Stress Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE