Accession Number:

ADA160829

Title:

A Model of Inhaled Gas and Vapor Transport in the Human Lung.

Descriptive Note:

Doctoral thesis,

Corporate Author:

AIR FORCE INST OF TECH WRIGHT-PATTERSON AFB OH

Personal Author(s):

Report Date:

1985-01-01

Pagination or Media Count:

134.0

Abstract:

The transport of inhaled gas or vapor in the human lung is theoretically modeled to determine the fraction of inhaled gas or vapor absorbed through the bronchial walls in the conductive zone and the fraction entering alveolated space and undergoing bloodgas exchange. An iterative-analytical approaches used, rather than a numerical one, to generate a large amount of data over a wide range of gas or vapor solubilities and diffusivities. The model applies to gases or vapors of low solubility. Simple analytical expressions are fitted to model results, expressing fractional bronchial absorption and alveolar uptake in terms of gas or vapor solubility and diffusivity. Typical physiological parameters are assumed and only physical properties of the gas or vapor are required for input. Methods are presented which allow estimation of these input values.

Subject Categories:

  • Anatomy and Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE