An Experimental Trial to Test the Efficacy of Temazepam to Induce Sleep and Improve Subsequent Performance during Partial Sleep Deprivation and Circadian Rhythm Desynchronosis.
AIR FORCE INST OF TECH WRIGHT-PATTERSON AFB OH
Pagination or Media Count:
This thesis presents a strategy for reducing jet lag induced performance degradations by resetting rhythms during prolonged rapid transmeridian flight is studied. Thirty-four aircrew member passengers on a C-141 flight were given temazepam or placebo during the flight from Oklahoma to Saudi Arabia for induction of sleep in a period compatible with sleep cycle at the destination, but out-of-sync with previous patterns set at home station, Mental performance and circadian rhythm patterns were tested per-flight, inflight and post-flight by several measurements including a computerized performance battery. The results indicated that in the temazepam group performance was improved to near baseline levels. The restorative power of temazepam induced sleep during a period of partial sleep deprivation and temazepams ability to reset circadian rhythms prior to arrival in the new time zone were demonstrated. Index words Restoril, Jet Lag, Transmeridian Flight.