Accession Number:

ADA160795

Title:

An Experimental Trial to Test the Efficacy of Temazepam to Induce Sleep and Improve Subsequent Performance during Partial Sleep Deprivation and Circadian Rhythm Desynchronosis.

Descriptive Note:

Master's thesis,

Corporate Author:

AIR FORCE INST OF TECH WRIGHT-PATTERSON AFB OH

Personal Author(s):

Report Date:

1985-06-01

Pagination or Media Count:

58.0

Abstract:

This thesis presents a strategy for reducing jet lag induced performance degradations by resetting rhythms during prolonged rapid transmeridian flight is studied. Thirty-four aircrew member passengers on a C-141 flight were given temazepam or placebo during the flight from Oklahoma to Saudi Arabia for induction of sleep in a period compatible with sleep cycle at the destination, but out-of-sync with previous patterns set at home station, Mental performance and circadian rhythm patterns were tested per-flight, inflight and post-flight by several measurements including a computerized performance battery. The results indicated that in the temazepam group performance was improved to near baseline levels. The restorative power of temazepam induced sleep during a period of partial sleep deprivation and temazepams ability to reset circadian rhythms prior to arrival in the new time zone were demonstrated. Index words Restoril, Jet Lag, Transmeridian Flight.

Subject Categories:

  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE