The Production of RhO(D) Negative Erythrocytes.
Annual rept. 1 Jul 84-30 Jun 85,
NEW YORK BLOOD CENTER N Y
Pagination or Media Count:
Attempts are being made to modify or destroy the Rh D antigen under conditions which will produce Rh negative erythrocytes of transfusable quality. To this end the effects of various lipase and membrane perturbants are being examined. Isolation and biochemical characterization of the D antigen is also being undertaken in order to gather information which will help formulate ways of modifying its expression. Originator-supplied keywords include Phospholipases and the modification of D antigenicity.