Accession Number:

ADA159356

Title:

Partial Purification and Properties of Bovine and Ovine Spinal Cord Acetylcholinesterases,

Descriptive Note:

Corporate Author:

DEFENCE RESEARCH ESTABLISHMENT SUFFIELD RALSTON (ALBERTA)

Personal Author(s):

Report Date:

1985-08-01

Pagination or Media Count:

22.0

Abstract:

Methods were developed for the solubilization of spinal cord acetylcholinesterases from cows and sheep. Several characteristics of this preparation are reported, including the results of attempts at purification. A method for bovine enzyme achieved an 80-fold purification from the spinal cord homogenate. Comparison studies with similiar enzymes from other species and tissues may help elucidate the mechanism of organophosphate poisoning.

Subject Categories:

  • Toxicology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE