Studies to Control Endemic Typhoid Fever in Chile
Rept. no. 2 (Annual) 1 Jan-31 Dec 1982
MARYLAND UNIV BALTIMORE CENTER FOR VACCINE DEVELOPMENT
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A multi-faceted program of applied research was undertaken to control endemic typhoid fever in Santiago, Chile. These studies included 1 A CaseControl study to identify risk factors and incriminate specific vehicles involved in transmission of S. typhi. 2 Prevalence of chronic S. typhi carriers in persons with cholecystitis. 3 Simple serologic and other screening tests to identify chronic S. typhi carriers. 4 A simple, practical, non- surgical treatment for chronic S. typhi carriers. 5 An evaluation of the sensitivity and specificity of diagnosing acute typhoid fever by identifying Vi antigen in urine. 6 A field-trial of Ty21a attenuated S. typhi vaccine. Keywords Salmonellosis Immunization and Epidemiology, and Vi antigen.
- Medicine and Medical Research