Accession Number:

ADA149658

Title:

Synthesis of New Prophylactic Antiradiation Drugs.

Descriptive Note:

Annual rept. 1 Aug 83-31 Jul 84,

Corporate Author:

ILLINOIS UNIV AT THE MEDICAL CENTER CHICAGO DEPT OF MEDICINAL CHEMISTRY

Personal Author(s):

Report Date:

1984-08-01

Pagination or Media Count:

64.0

Abstract:

Syntheses of 1-amino-2-1-phenyl-2-adamantylethane, 1-phenyl-4-adamantyl-methylamine and 1-amino-2- 4-1-adamantylphenyl ethane and their transformation to the disulfides of the corresponding 2-mercaptoacetamidines are described. 4-Epoxymethyleneprotoadamantane was converted in 2 steps to 2-phenyl-1-adamantanecarboxylic acid, a precursor for the planned synthesis of 2-phenyl-1-adamantylalkylamines.

Subject Categories:

  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE