Accession Number:

ADA148651

Title:

The Use of ATP-MgCl2 in the Treatment of Injury and Shock.

Descriptive Note:

Annual rept. 1 Sep 82-31 Aug 83,

Corporate Author:

YALE UNIV NEW HAVEN CONN DEPT OF SURGERY

Personal Author(s):

Report Date:

1983-08-31

Pagination or Media Count:

12.0

Abstract:

In conscious rate and primates, bolus infusion of the entire efficacious dose of ATP-MgCl2 transiently decrease mean blood pressure but there were no long term side effects and there were no mortalities. Moreover, daily administration of the entire efficacious dose of ATP-MgCl2 for a period of three months in rats did not produce any mortality or adverse side effects. ATP-MgCl2 was approved for clinical studies by the Food and Drug Administration of the U.S. Armys and our Human Investigation Committee.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE