Rapid Diagnosis of Arbovirus and Arenavirus Infections by Immunofluorescence.
Annual progress rept. 1 Sep 81-31 Jan 82,
YALE UNIV NEW HAVEN CONN SCHOOL OF MEDICINE
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A serologic survey of equatorial Africa for antibodies in man to Crimeanhemorrhagic fever-Congo, Rift valley fever, Ebola, Lassa fever, and Marburg viruses was begun. Positive reactions to Ebola virus have been observed with sera from military recruits from southern Sudan 41.3 but rarely with sera from military recruits from northern Sudan 1.5. Ebola positive reactions have also been found in sera from life-long residents of Senegals lower Fleuve region in the Senegal River Valley. Antibody to Rift Valley Fever and Lassa viruses was also found in Senegal. Human sera from Ethiopia and Senegal have been screened on polyvalent spot-slides. The rate of positive reaction varies with geographic region. One hundred and fifty-eight 158 bunyavirus supergroup viruses have been screened for reaction on KHF virus-infected spot-slides. Positive reactions have been found with several group Tete viruses and with one antibody preparation to Manawa virus.
- Medicine and Medical Research