Accession Number:

ADA141471

Title:

Preparation of a Homologous (Human) Intravenous Botulinal Immune Globulin.

Descriptive Note:

Final comprehensive rept. 1 Jul 81-30 Nov 82,

Corporate Author:

MINNESOTA UNIV MINNEAPOLIS

Personal Author(s):

Report Date:

1983-05-01

Pagination or Media Count:

243.0

Abstract:

An intravenous, botulinal, immune human globulin has been prepared from human immune plasma supplied by the United States Army Medical Research Institute of Infectious Diseases USAMRIID at Fort Detrick, Frederick, Maryland, and contains neutralizing activity to five botulinal neurotoxins A, B, C, D and E. This final report contains details of all source materials, methods, procedures, testing and status of four lots of human, intravenous, hyperimmune, pentavalent, botulinal IgG that have been prepared and shipped to USAMRIID. These include lots IVBG-1A-553 grams, IVBG-1B--579 grams, IVBG-2A--563 grams, and IVBG-2B-401 grams for a total of 2096 grams. The information included in this report contains all the documentation required of products prepared for Investigational New Drug IND status.

Subject Categories:

  • Biochemistry
  • Medicine and Medical Research
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE