Motor Performance in Irradiated Rats as a Function of Radiation Source, Dose, and Time Since Exposure.
Final rept. Jan 83-Jan 84,
SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TX
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The study reported here has employed a single species rats and a single motor task rotarod, and has evaluated performance as a function of time after irradiation exposure across a fixed dose range 0-1200 rads using four radiation sources electrons, neutrons, protons, and X-rays. Only minor differences in performance were noted as a function of radiation source, with neutrons producing the largest deficits. All sources produced a clear dose-response curve for each of the four times 1, 8, 15, and 22 days after irraditaion. The LD5015 for the various exposures were found to be X-rays, 1125 rads electrons, 810 rads protons, 675 rads and neutrons, 265 rads.