Accession Number:

ADA141024

Title:

Mutagenic Activity of Dimethylsulfoxide (DMSO) Solvent Samples from Munition Pilot Test Plant on Mammalian Cells

Descriptive Note:

Final rept. Sep 1982-Jun 1983

Corporate Author:

CALIFORNIA UNIV DAVIS LAB FOR ENERGY-RELATED HEALTH RESEARCH

Report Date:

1983-06-01

Pagination or Media Count:

12.0

Abstract:

Two DMSO solvent samples containing munition constituents contained a direct-acting mutagens. Of the two samples, DMSO recycle solvent sample had a more acute mutagenic activity than DMSO evaporator sludge sample at comparable dilution of the stock solution. The mutagenic activity in these samples was not augmented with addition of rat liver S-9. Since these samples are a mixture of several compounds, the identity of the specific compounds responsible for the mutagenic activity is not known.

Subject Categories:

  • Medicine and Medical Research
  • Toxicology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE