Aerosol Direct Fluorination: Syntheses of the Highly Branched Ketones, F-Pinacolone and F-Provalone.
TENNESSEE UNIV KNOXVILLE DEPT OF CHEMISTRY
Pagination or Media Count:
The extension direct fluorination techniques to the syntheses of the here-to-fore unknown highly branched perfluoroketones F-3,3-dimethyl-2-butanone F-pinacolone and F-2,2,5-trimethyl-3-hexanone F-provalone from 3,3-dimethyl-2-butanone pinacolone and 2,2,4,4-tetramethyl-3-pentanone pivalone respectively demonstrates again the efficacy of the aerosol direct fluorination process for the synthesis of perfluoroketones directly from ketones. The interesting rearrangement of the hydrocarbon di-tert-butyl ketone pivalone to the perfluorinated tert-butyl ketone, F-provalone is unprecedented in our experience and does not occur at the monofluorination step but later in the fluorination. Isolated yields of 12 and 9 though modest are unadjusted by physical losses of recoverable hydrocarbons present at the termination of the reaction. Perfluorinated product distributions, concentrations of products collected from the reactor effluent, are 23 and 71 of the total material traversing the reactor. Author
- Organic Chemistry
- Physical Chemistry