Accession Number:

ADA136706

Title:

The Role of Intestinal Bacteria in Acute Diarrheal Diseases

Descriptive Note:

Annual rept. Jul 1975-Jun 1977

Corporate Author:

TUFTS-NEW ENGLAND MEDICAL CENTER BOSTONMA

Personal Author(s):

Report Date:

1977-09-01

Pagination or Media Count:

35.0

Abstract:

This report describes investigations in these four major areas of research 1 Reassessment of the infant rabbit model of E. coli colonization. 2 Testing of E. coli strains isolated from humans with diarrheal disease for enterotoxin production and presence of colonization-specific surface antigens. 3 Methodology for isolation of specific pili i.e. surface antigens which function in colonization. Characterization of pili. Preparation of pili- specific antisera. 4 In vitro adhesion assays specific for recognition of E. coli strains which are potentially pathogenic for humans.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE